PI: Helena Schmidt
Focus: Genetic epidemiology plays a central role in precision medicine. It investigates the association between genomic variants and risk for diseases and identifies „high impact targets“ for therapy and prevention. Our research focus is on human aging. In Europe 90% of the mortality is explained by aging. By slowing down the aging process itself, humans could achieve a long and healthy life. Our research aims are:
- Identification of genetic variants, genes & pathways involved in human aging in order to better understand core processes of aging I
- Exploring the interaction of genetic, lifestyle & environmental factors in order to develop strategies modulating aging at the individual as well as community level.
Our laboratory is certified according to the international standard ISO 9001: 2015.
Network: We apply an amalgam of methods such as epidemiology, statistics, bioinformatics, and genomics and act in a multidisciplinary environment. Our local partners are research teams from the MUG, UniGraz, FH Joanneum and the City of Graz. We initiated the genetic epidemiological studies in frame of the Austrian Stroke Prevention Study (ASPS), ADSPS-Family and the Graz Study on Health & Aging, all cohort studies on aging in Graz. Wer are member of numerous international consortia including The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), International Genomics of Alzheimer’s Project (IGAP), und die vom The EU Joint Programme – Neurodegenerative Disease Research (JPND) finanzierte European Alzheimer Disease DNA Biobank (EADB) bzw. BRain Imaging, Cognition, Dementia und next generation Genomics (BRIDGET).