25^th - 27^th September 2023
Seggau Castle

Monday, 25th of September
14:25	Opening & Welcome Notes by the Speaker
14:30 - 16:00	Session 1 chaired by: Manu Kanti
14:30 - 14:50	Sophie Honeder: Activity-based proteomic profiling reveals reduction of lipid hydrolase activity levels in lung tumors
14:50 – 15:10	Sarah Masser: Characterizing human PRMT – kinase interactions with a specific focus on PRMT5
15:10 – 15:30	Katharina Jonas: MiR-4646-5p acts as a tumor-suppressive factor in triple negative breast cancer by targeting the cholesterol transport protein GRAMD1B
15:30 – 15:50	Furkan E. Oflaz: Annexin-A5 is fundamental for VDAC1-dependent mitochondrial Ca2+ homeostasis and determines the susceptibility to apoptosis
15:50 – 16:10	Paola Peña de la Sancha: Adipose triglyceride lipase derived fatty acids control sterol regulatory element-binding protein-1c driven hepatic lipogenesis
16:10 - 16:40	Break
16:40 - 18:00	Session 2 chaired by: Felix Prinz
16:40 - 17:00	Joshua A. Babalola: Neuroprotective effects of Astaxanthin in preclinical models of Alzheimer’s disease
17:00 - 17:20	Alina Jamnik: Ces2a deficiency provokes hepatic steatosis in mice
17:20 - 17:40	Sinem Usluer: Disordered regions mediate the interaction of p53 and MRE11
17:40 - 18:00	Anna Tilp: Chylomicron treatment of endothelial cells causes the release of small extracellular vesicles that stimulate lipid accumulation and pro-inflammatory pathways in underlying cells
18:00 - 19:00	Dinner
19:00 - 21:00	Poster & Wine
	Sophie Honeder Sarah Masser Katharina Jonas Furkan E. Oflaz Paola Peña de la Sancha Joshua A. Babalola	Alina Jamnik Sinem Usluer Anna Tilp Michelle Reynders Martin Bürger
Tuesday, 26th of September
09:30 - 10:30	Faculty Meeting
10:30 - 11:50	Session 3 chaired by: Paola Peña de la Sancha
10:30 - 10:50	Michelle Reynders: Liver-adipose tissue communication through mTORC1
10:50 - 11:10	Martin Bürger: Elucidating the consequences of MMP-12 loss in lysosomal acid lipase deficiency
11:10 - 11:30	Manu M. Kanti: Adipose triglyceride lipase (ATGL) mediated lipid metabolism fuels lung regeneration
11:30 - 11:50	Vanessa Jäger: Oncogene or tumor-suppressor? - Functional characterization of the plasma membrane rupture mediator Ninjurin 1 in lung cancer
12:00 - 13:00	Lunch
13:00 - 14:40	Session 4 chaired by: Katharina Jonas
13:00 - 13:20	Alena Akhmetshina: Loss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles
13:20 - 13:40	Martin Hirtl: Super-resolution microscopy unveils intricate differences in sub-organelle distribution dynamics of MCU between excitable and non-excitable cells
13:40 - 14:00	Aneta Lenard: Optofluidic force induction enables quantitative analysis of size distribution and kinetics of biomolecular condensates
14:00 - 14:20	Felix Prinz: MicroRNA mimics can distort physiological microRNA effects on immune checkpoints by triggering an antiviral interferon response
15:00	Bus transfer - Styrian Fruit and Wine Trail Silberberg
17:30	Joint dinner at "Landgasthof Wratschko"
Wednesday, 27th of September
09:00 - 10:40	Session 5 chaired by: Joshua A. Babalola
09:00 - 09:20	Selena Trattner: Dietary protection against cognitive decline in Alzheimer’s disease mouse model by targeting polyamine pathway
09:20 - 09:40	Qishun Zhou: Tyrosine-mediated nuclear import of CIRBP reveals an alternative NLS recognition mechanism by TNPO3
09:40 - 10:00	Valentina Bianco: Regional differences in the small intestine proteome of control mice and of mice lacking lysosomal acid lipase
10:00 - 10:20	Olaf Bachkönig: Risperidones effect on the H1 receptor reveals a nonlinear relationship between cytosolic Ca2+ and mitochondrial Ca2+ uptake
10:20 - 10:40	Martina Bergmann: A novel platform for testing synergistic effects of anti-aging drugs
10:40 - 12:00	Poster & Coffee
	Felix Prinz Alena Akhmetshina Martin Hirtl Aneta Lenard Manu M. Kanti	Selena Trattner Qishun Zhou Valentina Bianco Olaf Bachkönig Martina Bergmann
12:00 - 12:30	Concluding Remarks
12:30	Lunch