12th Scientific Retreat
19th - 20th October 2022
Seggau Castle
11:00 Opening & Welcome Notes by the Speaker 11:00 - 12:00 Session 1
chaired by: Valentina Bianco & Denis Krivic11:00 - 11:20 Martin Buerger: Elucidating the consequences of MMP12 loss in lysosomal acid lipase deficiency 11:20 - 11:40 Sinem Usluer: Interaction between p53 and MRE11 is regulated by transactivation domain of p53 and GAR domain of MRE11 11:40 - 12:00 Zhanat Koshenov: Presenilin-1 controls pancreatic beta-cell metabolism by regulating mitochondrial Ca2+ sensitive NADH shuttles 12:30 - 14:00 Lunch 14:00 - 15:20 Session 2
chaired by: Anna Tilp & Sinem Usluer14:00 - 14:20 Aneta Lenard: Deciphering structural and functional effects of protein citrullination 14:20 - 15:20 Keynote lecture:
Prof. Dr. Boudewijn M.T. Burgering: FOXO transcription factors new insights in structure and function
Department Molecular Cancer Research, Center for Molecular Medicine, UMC Utrecht, The Netherlands15:20 - 15:50 Break 
15:50 - 17:10 Session 3
chaired by: Paola Peņa de la Sancha & Zhanat Koshenov15:50 - 16:10 Alena Akhmetshina: Role of lysosomal acid lipase deficiency in skeletal muscle formation, development, and metabolism 16:10 - 16:30 Vanessa Jaeger: Uncovering innovative molecular targets for lung cancer therapy on the highly recurrent chromosomal gain of 1q21 16:30 - 16:50 Anna Tilp: The role of human adipose triglyceride lipase in cardiac lipid metabolism 16:50 - 17:10 Hermann Habacher: Establishing the Wnt-p53 intersection as a novel drug target 18:00 - 19:00 Dinner 19:00 - 21:00 Poster & Wine 
09:00 - 10:00 Faculty Meeting 10:00 - 11:40 Session 4
chaired by: Vanessa Jaeger & Martin Buerger10:00 - 10:20 Valentina Bianco: Impact of (intestinal) LAL deficiency on lipid metabolism, immune cell infiltration and gut microbiota 10:20 - 11:00 Alumni lecture:
Katharina Huber, PhD: What's next after your PhD? Career path in pre-clinical and clinical research
Division of Oncology, Medical University of Graz11:00 - 11:20 Denis Krivic: New avenues for photopharmacological control over basophilic and mast cell function 11:20 - 11:40 Paola Peña de la Sancha: Adipose triglyceride lipase derived fatty acids control sterol element-binding protein-1c driven hepatic lipogenesis 11:40 Concluding Remarks 12:30 Joint lunch at the restaurant "Das Kappel" 
