DK-MCD Retreat 2017

9^th - 11^th October 2017
Oststeirischer Hof, Söchau

Monday, 9^th of October

14:00 - 14:30 Opening & Welcome Notes by the Speaker and Students' speakers

Self-presentation of the new DK-MCD students:

Benedikt Kien

Katharina Walter

Alex Zaufel

Gabriel Zirkovits

14:30 - 15:50 Session 1
chaired by: Oleksandra Tiapko & Tamara Tomin

14:30 - 14:50 Isabelle Strießnig-Bina: ATGL deficiency leads to lung cancer in mice

14:50 - 15:10 Madalina Duta-Mare: Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis

15:10 - 15:30 Elham Fanaee-Danesh: Bexarotene (Bex) and astaxanthin (Asx) modulate cholesterol and amyloid-beta metabolism in cerebrovascular endothelial cells

15:30 - 15:50 Markus Plank: Letm1-dependent ROS shuttling affects mitochondrial calcium uptake

15:50 - 16:10 Barbora Svobodova: New insights into the molecular principles of lipid recognition and in lipid gating in TRPC channels

16:10 - 16:40 Break

16:40 - 18:30 Session 2
Madalina Duta-Mare & Christina Leopold

16:40 - 17:10 Alumni Lecture:
Michael Schwarzl: Haemodynamics in heart failure: The role of cardiovascular risk factors
University Heart Center Hamburg Eppendorf, Department of General and Interventional Cardiology, Hamburg, Germany

17:10 - 17:30 Lisa Maresch: Cloning and characterization of an unknown carboxylesterase (Ces2c) in liver and small intestine

17:30 - 17:50 Alex Zaufel: Inhibition of the mechanistic target of rapamycin complex 1 (mTORC1) reduces transcriptional activity of the farnesoid X receptor (FXR)

17:50 - 18:10 Katharina Kainz: Natural killers: dietary polyphenols as novel antifungal agents

18:10 - 18:30 Benedikt Kien: Investigating the role of the lipid droplet-coating protein perilipin 5 in mitochondrial dynamics and redox signaling

18:30 - 19:30 Dinner

19:30 - 21:00 1^st Poster Session: Science & Wine

Isabelle Strießnig-Bina
Madalina-Cristina Duta-Mare
Elham Fanaee-Danesh
Markus Plank
Barbora Svobodova Lisa Maresch
Alex Zaufel
Katharina Kainz
Benedikt Kien

Tuesday, 10^th of October

10:00 - 11:00 Session 3
chaired by: Benjamin Gottschalk & Markus Plank

10:00 - 10:20 Jelena Tadic: Improving sleep quality: Screen of natural compounds

10:20 - 10:40 Christiane Klec: Linking diabetes with Alzheimer’s disease: Presenilin-1-mediated ER Ca²⁺ leak is an essential trigger for β-cell responsiveness to glucose

10:40 - 11:00 Yidan Sun: Human fetoplacental endothelium adapts its cholesterol homeostatic mechanisms to gestational diabetes mellitus through ROS-generated oxysterols

11:00 - 11:30 Break

11:30 - 12:30 Session 4
chaired by: Barbora Svobodova & Alex Zaufel

11:30 - 11:50 Stephanie Kolleritsch: The impact of perilipin 5 on cardiac energy metabolism

11:50 - 12:10 Christina Leopold: Consequences of lysosomal acid lipase deficiency on lipid and carbohydrate metabolism

12:10 - 12:30 Gabriel Zirkovits: Abhydrolase domain containing 15 (ABHD15) influences liver metabolism

12:30 - 13:30 Lunch

13:30 - 14:30 Parallel Meetings of the Faculty and Students’ Faculty

15:00 Departure by bus

16:00 - 17:30 Guided Tour at the Castle Riegersburg

18:00 Joint Dinner at the Restaurant Lasslhof

Wednesday, 11^th of October

09:00 - 10:40 Session 5
chaired by: Benedikt Kien & Lisa Maresch

09:00 - 09:20 Tamara Tomin: Role of lipolysis in cancer

09:20 - 09:40 Benjamin Gottschalk: Dynamic assembly of the mitochondrial calcium uniporter in the inner boundary membrane

09:40 - 10:00 Katharina Walter: N-Acetylaspartate: a brain metabolite found in tumors

10:00 - 10:20 Lei Liu: Molecular regulation of adrenal function by bile acids

10:20 - 10:40 Oleksandra Tiapko: Identification of lipid binding site in two-pore-domain potassium channels with photoswitchable lipids

10:40 - 11:00 Beatrix Wieser: Regulation of sterol regulated element binding proteins by lipolysis products

11:00 - 12:30 2^nd Poster Session: Science & Drinks

Jelena Tadic
Christiane Klec
Yidan Sun
Stephanie Kolleritsch
Christina Leopold
Gabriel Zirkovits Tamara Tomin
Benjamin Gottschalk
Katharina Walter
Lei Liu
Oleksandra Tiapko
Beatrix Wieser

12:30 - 13:00 Consortium Meeting & Concluding Remarks

13:00 - 14:00 Lunch

Monday, 9^th of October
14:00 - 14:30	Opening & Welcome Notes by the Speaker and Students' speakers
	*Self-presentation of the new DK-MCD students:* Benedikt Kien Katharina Walter Alex Zaufel Gabriel Zirkovits
14:30 - 15:50	Session 1 chaired by: Oleksandra Tiapko & Tamara Tomin
14:30 - 14:50	Isabelle Strießnig-Bina: ATGL deficiency leads to lung cancer in mice
14:50 - 15:10	Madalina Duta-Mare: Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis
15:10 - 15:30	Elham Fanaee-Danesh: Bexarotene (Bex) and astaxanthin (Asx) modulate cholesterol and amyloid-beta metabolism in cerebrovascular endothelial cells
15:30 - 15:50	Markus Plank: Letm1-dependent ROS shuttling affects mitochondrial calcium uptake
15:50 - 16:10	Barbora Svobodova: New insights into the molecular principles of lipid recognition and in lipid gating in TRPC channels
16:10 - 16:40	Break

16:40 - 18:30	Session 2 Madalina Duta-Mare & Christina Leopold
16:40 - 17:10	Alumni Lecture: Michael Schwarzl: Haemodynamics in heart failure: The role of cardiovascular risk factors University Heart Center Hamburg Eppendorf, Department of General and Interventional Cardiology, Hamburg, Germany
17:10 - 17:30	Lisa Maresch: Cloning and characterization of an unknown carboxylesterase (Ces2c) in liver and small intestine
17:30 - 17:50	Alex Zaufel: Inhibition of the mechanistic target of rapamycin complex 1 (mTORC1) reduces transcriptional activity of the farnesoid X receptor (FXR)
17:50 - 18:10	Katharina Kainz: Natural killers: dietary polyphenols as novel antifungal agents
18:10 - 18:30	Benedikt Kien: Investigating the role of the lipid droplet-coating protein perilipin 5 in mitochondrial dynamics and redox signaling
18:30 - 19:30	Dinner
19:30 - 21:00	1^st Poster Session: Science & Wine
	Isabelle Strießnig-Bina Madalina-Cristina Duta-Mare Elham Fanaee-Danesh Markus Plank Barbora Svobodova	Lisa Maresch Alex Zaufel Katharina Kainz Benedikt Kien

Tuesday, 10^th of October
10:00 - 11:00	Session 3 chaired by: Benjamin Gottschalk & Markus Plank
10:00 - 10:20	Jelena Tadic: Improving sleep quality: Screen of natural compounds
10:20 - 10:40	Christiane Klec: Linking diabetes with Alzheimer’s disease: Presenilin-1-mediated ER Ca²⁺ leak is an essential trigger for β-cell responsiveness to glucose
10:40 - 11:00	Yidan Sun: Human fetoplacental endothelium adapts its cholesterol homeostatic mechanisms to gestational diabetes mellitus through ROS-generated oxysterols
11:00 - 11:30	Break
11:30 - 12:30	Session 4 chaired by: Barbora Svobodova & Alex Zaufel
11:30 - 11:50	Stephanie Kolleritsch: The impact of perilipin 5 on cardiac energy metabolism
11:50 - 12:10	Christina Leopold: Consequences of lysosomal acid lipase deficiency on lipid and carbohydrate metabolism
12:10 - 12:30	Gabriel Zirkovits: Abhydrolase domain containing 15 (ABHD15) influences liver metabolism
12:30 - 13:30	Lunch
13:30 - 14:30	*Parallel Meetings of the Faculty and Students’ Faculty*
15:00	Departure by bus
16:00 - 17:30	Guided Tour at the Castle Riegersburg
18:00	Joint Dinner at the Restaurant Lasslhof

Wednesday, 11^th of October
09:00 - 10:40	Session 5 chaired by: Benedikt Kien & Lisa Maresch
09:00 - 09:20	Tamara Tomin: Role of lipolysis in cancer
09:20 - 09:40	Benjamin Gottschalk: Dynamic assembly of the mitochondrial calcium uniporter in the inner boundary membrane
09:40 - 10:00	Katharina Walter: N-Acetylaspartate: a brain metabolite found in tumors
10:00 - 10:20	Lei Liu: Molecular regulation of adrenal function by bile acids
10:20 - 10:40	Oleksandra Tiapko: Identification of lipid binding site in two-pore-domain potassium channels with photoswitchable lipids
10:40 - 11:00	Beatrix Wieser: Regulation of sterol regulated element binding proteins by lipolysis products
11:00 - 12:30	2^nd Poster Session: Science & Drinks
	Jelena Tadic Christiane Klec Yidan Sun Stephanie Kolleritsch Christina Leopold Gabriel Zirkovits	Tamara Tomin Benjamin Gottschalk Katharina Walter Lei Liu Oleksandra Tiapko Beatrix Wieser
12:30 - 13:00	Consortium Meeting & Concluding Remarks
13:00 - 14:00	Lunch