2nd Scientific Retreat
25th - 27th October 2012
Seggau Castle
14:00 - 14:30 Opening & Welcome Notes Session 1
chaired by: Katarina Fritz & Wael Al Zoughbi14:30 - 15:15 KeyNote Lecture:
Tak W. Mak: Cancer Metabolism: Back to the Future
The Campbell Family Institute for Breast Cancer Research, Division of Stem Cell and Develop-mental Biology, Advanced Medical Discovery Institute/Ontario Cancer Institute, Toronto, Canada15:15 - 15:30 Maryam Heidary: Characterization of CTCs with stem cell features from patients with breast cancer 15:30 - 15:45 Jelena Belić: Characterization of circulating tumor cells and plasma DNA in patients with prostate cancer 15:45 - 16:00 Sumitra Mohan: Analysis of circulating cell free tumor DNA in plasma in colon cancer patients 16:00 - 16:30 Break Session 2
chaired by: Nina Pollak & Anita Sahu16:30 - 16:45 Pooja Lahiri: p62/Sequestosome-1: A crucial player of Mallory-Denk body formation 16:45 - 17:00 Anita Kuldeep Mehta: Steatohepatitis-driven hepatocellular carcinoma: A keratinopathy 17:00 - 17:15 Anil Butchi Reddy: Molecular mechanisms of Nor-ursodeoxycholic acid (Nor-UDCA) in non-alcoholic fatty liver disease (NAFLD) and metabolically induced liver cancer 17:15 - 17:30 Michaela Mueller: Effects of high levels of ursodeoxycholic acid in morbidly obese patients 17:30 - 17:45 Ge Jin: Pathophysiological modifiers of intracellular Ca2+ handling and triggered arrhythmias 17:45 - 18:00 Michael Schwarzl: A risk factor-based porcine model of early heart failure with preserved ejection fraction (HFpEF) 18:00 - 19:00 FACULTY MEETING 19:00 - 20:00 Dinner Session 3
chaired by: Gerald Hoefler20:00 - 21:00 Career Lecture:
Jan Eggermont: Surviving in the 21st century knowledge society: Welcome to the VUCA world
Laboratory of Cellular Transport Systems, Katholieke Universiteit Leuven, Leuven, Belgium- open end Get together
Session 4
chaired by: Stefanie Schlager & Vinay Sachdev09:00 - 09:45 KeyNote Lecture:
Veronika Sexl: NK cell mediated tumor surveillance: STATs in the spotlight
Institute of Pharmacology and Toxicology, University of Veterinary Medicine Vienna, Austria09:45 - 10:00 Wael Al Zoughbi: ATGL downregulation enhances tumor growth 10:00 - 10:15 Ganapathy Shanmugam Paramasivan: The role of metabolic lipases in the pathogenesis of malignant tumors 10:15 - 10:30 Jianfeng Huang: The role of PPARα in Atgl mediated tumor progression 10:30 - 11:00 Break Session 5
chaired by: Anita Kuldeep Mehta & Pooja Lahiri11:00 - 11:15 Nemanja Vujić: Is DGAT1 inhibition a potential target to ameliorate atherosclerosis? 11:15 - 11:30 Madeleine Goeritzer: Intact mitochondria despite triglyceride accumulation in CGI-58-/- macrophages 11:30 - 11:45 Vinay Sachdev: Link between triacylglyerol synthesizing enzymes and cholesterol metabolism 11:45 - 12:00 Stefanie Schlager: Characterization of platelet function in adipose triglyceride lipase-deficient mice 12:00 - 12:15 Anil Paul Chirackal Manavalan: Phospholipid transfer protein is expressed in cerebrovascular endothelial cells and involved in HDL genesis at the blood brain barrier 12:15 - 12:30 Alexandra Kober: ATP-binding cassette transporter G1 and apolipoprotein M are ‘novel players’ in cholesterol transport at the blood-brain barrier 12:30 - 13:30 Lunch Session 6
chaired by: Madeleine Goeritzer & Nemanja Vujić13:30 - 13:45 Nina Pollak: Characterization of mice overexpressing myocardial lipid droplet protein (MLDP) in cardiac muscle 13:45 - 14:00 Manoja K. Brahma: Implications of fibroblast growth factor 21 (FGF21) on cardiac energy metabolism 14:00 - 14:15 Helmut Pelzmann: The N-acetylaspartate pathway: New implications in brown adipose tissue and a connection to PPARα singalling 14:15 - 14:30 Ariane Klatzer: N-acetyltransferase 8-like, a mitochondrial protein, accelerates brown adipose tissue metabolism 14:30 - 15:00 Break Session 7
chaired by: Michael Schwarzl & Ge Jin15:00 - 15:15 Shaymaa Bahnassy: Stretch-induced activation of NFAT in HL-1 atrial myocytes 15:15 -15:30 Michaela Lichtenegger: Engineering of the TRPC3 pore reveals molecular determinants of cation selectivity and gating 15:30 - 15:45 Claire Jean-Quartier: A novel UCP interacting protein is involved in motochondrial Ca2+ uptake 15:45 - 16:00 Neelanjan Vishnu: Spatio-temporal correlations between Ca2+ and ATP in the lumen of the endoplasmic reticulum 17:00 - 18:00 Guided Tour at the Destillery Weutz 18:30 - 22:00 Joint Dinner in the Restaurant Staribacher 
Session 8
chaired by: Claire Jean-Quartier & Neelanjan Vishnu09:00 - 09:45 KeyNote Lecture:
Valter Longo: Differential stress resistance and sensitization in cancer treatment
Davis School of Gerontology, University of Southern California, Los Angeles, USA09:45 - 10:00 Cornelia Sommer: Vms1 as a novel protector in aging and disease 10:00 - 10:15 Lukas Habernig: Yeast as a model for pParkinson disease-spotlighting α–synuclein 10:15 - 10:30 Ali Alavian Ghavanini: Hypochlorous acid induces the apoptotic machinery in yeast 10:30 - 11:00 Break Session 9
chaired by: Ariane Klatzer & Helmut Pelzmann11:00 - 11:15 Chintan Koyani: Signalling cascades in cardiomyocytes in response to HOCl-modified LDL 11:15 - 11:30 Katarina Fritz: Altered protein expression in adipose triglyceride lipase knockout B-cell tumours 11:30 - 11:45 Pål William Wallace: Discovery of novel polyesterases using activity based proteomics 11:45 - 12:00 Anita Sahu: qProteomics on PLIN1 mutant lipid droplets using SILAC labelling 12:00 - 13:00 CONSORTIUM MEETING 13:00 - 14:00 Lunch 
